Pharmaceutical Preformulation Notes pdf

Pharmaceutical Preformulation

Preformulation involves the application of biopharmaceutical principles to the physicochemical parameters of drug substance are characterized with the goal of designing optimum drug delivery system.

Before beginning the formal preformulation programs the preformulation scientist must consider the following factors:-

- The amount of drug available.

- The physicochemical properties of the drug already known.

- Therapeutic category and anticipated dose of compound.

- The nature of information, a formulation should have or would like to have.