Pharmacodynamics

Content

General Pharmacology

       Principles of drug action

       Mechanisms involved in drug action

       Enzyme inhibition

       Receptor

       Structure of G – Protein coupled receptor

       Effector pathways of GPCR

       Ion channel receptor, enzyme linked receptor

       Receptors regulating gene expression

       Functions of receptors

       Synergism and antagonism

Intended Learning Outcomes

At the end of this lecture, student will be able to

       Explain principles of drug action

       Explain mechanisms involved in drug action

       Describe enzyme inhibition process

       Describe Receptor

       Describe G – Protein coupled receptor

       Explain effector pathways of GPCR

       Describe ion channel receptor, enzyme linked receptor and  receptors regulating gene expression

       Explain the functions of receptors

       Differentiate between synergism and antagonism

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