Herbal Drug industries and Research Institutions

Herbal Drug industries and Research Institutions

Objective

At the end of this lecture, student will be able to

• Recognize various herbal drug industries

• Identify herbal research institutions involved in the herbal drug research

Herbal Drug Industries

Name of the company	Examples of products
Himalaya Drug Company	Liv 52, Bonnisan, Mentat, Septilin
Dabur Pharmaceuticals	Chyawanprash, Hajmola, Pudinhara
Emami Drugs	Navaratna oil, Boroplus, Fast relief
Baidyanath	Chyawanprash, Mahabhringharaj oil
Pankaja kasturi Pharmaceuticals	Pankaja kasturi breath, Mygrane oil
Zandu Pharmaceuticals	Triphala Guggul, Pancharista, Keasri jeevan
Cholayil Pharmaceuticals	Rumacide G, Medimix, cuticura talc

Himalaya Drug Company

Ø Himalaya's story began way back in 1930

Ø A curious young man riding through the forests of Burma saw restless elephants being fed the root of a plant, Rauwolfia serpentina, which helped pacify them

Ø Fascinated by the plant's effect on elephants, this young man, Mr. M. Manal, the founder of Himalaya, wanted to scientifically test the herb's properties

Ø With no money and only a pocketful of dreams, he pawned his mother's jewellery to buy a hand-operated tableting machine

Ø He spent his days learning about herbs from neighbourhood healers

Ø His vision was to 'bring the traditional Indian science of Ayurveda to society in a contemporary form‘

Ø After four years of researching the herb Rauwolfia serpentina, Serpina, the world's first natural antihypertensive drug was launched in 1934.

Ø The discovery set the future course for Himalaya

Ø In 1955, Himalaya introduced Liv. 52, a liver formulation that ensures optimum liver function and the product soon became top selling herbal medicine

Ø Other brands soon followed including Cystone, Bonnisan and Rumalaya forte, products that went on to become household names

Ø Today, the Himalaya brand is synonymous with safe and efficacious herbal products

Ø Starting off operations in Dehradun way back in the 1930s, the company later spread its wings to Mumbai and across the country. In 1975, the company set up an advanced manufacturing facility in Makali, Bengaluru, India. In 1991, the company relocated its R&D facility to Bengaluru

Abana:

• Arjuna - Potent hypolipidemic responsible for reducing total cholesterol and triglyceride levels, thereby helping in the management of atherosclerosis. As a cardioprotective, the herb prevents oxidative damage to the heart and stabilizes blood pressure.

• Indian Bdellium (Guggul) effectively lowers triglyceride levels, total cholesterol levels and free fatty acid levels, through liver lipolysis

Diabecon

• Shilajeet decreases hepatic glucose production and prevents hyperglycemia.

• Gymnema’s (Meshashringi) principal constituent is gymnemic acid, which has antidiabetic properties. It reduces excessive blood sugar. It also has a regenerative effect on pancreatic beta cells

• Indian Kino Tree’s (Pitasara) principal constituent, epicatechin, has alpha-glucosidase inhibitory properties and regularizes key metabolic enzymes involved in carbohydrate metabolism

Gasex Tablet

Ø Improves digestion

Ø Gasex Tablet renormalizes the intestinal transit time. Gasex tablet has prebiotic, antiflatulent and antacid, antiulcer, anti-inflammatory, hepatoprotective, cholagogue and membrane-modulating, antimicrobial, and antioxidant actions

Ø Gasex Tablet exerts carminative and antispasmodic actions that support the digestive function

Dabur Pharmaceuticals

Ø Dabur India Ltd. is one of India’s leading FMCG Companies with Revenues of over Rs 7,680 Crore & Market Capitalisation of over Rs 48,800 Crore.

Ø Dabur India is also a world leader in Ayurveda with a portfolio of over 250 Herbal/Ayurvedic products. Dabur's FMCG portfolio today includes five flagship brands with distinct brand identities -- Dabur as the master brand for natural healthcare products, Vatika for premium personal care, Hajmola for digestives, Réal for fruit juices and beverages and Fem for fairness bleaches and skin care products

Ø Dabur's products also have huge presence in the overseas markets and are today available in over 120 countries across the globe. Its brands are highly popular in the Middle East, SAARC countries, Africa, US, Europe and Russia

Ø The 132-year-old ayurvedic company, promoted by the Burman family, started operating in 1884 as an Ayurvedic medicines company

Ø Dabur today operates in key consumer product categories like Hair Care, Oral Care, Health Care, Skin Care, Home Care and Foods. The Ayurvedic company has a wide distribution network, covering 6 million retail outlets with a high penetration in both urban and rural markets

Dabur Chyawanprash – One of the Best Ayurvedic Chyawanprash

Ø Derived from 2,500-year-old Ayurvedic formula

Ø Totally chemical-free, natural and safe

Ø Combination of herbs and plant extracts in a base of Amla fruit pulp

Ø Dabur Chyawanprash has a tangy sweet-sour taste and the consistency of jam. It can be taken directly or with milk and as bread spread.

Dabur's Honitus Cough Syrup

• Provides effective relief from cough, without side-effects

• Dabur Honitus Cough Syrup is an ayurvedic medicine for cough that is fortified with Tulsi , Mulethi & Banapsha and other powerful scientifically proven medicinal plants as recommended by Ayurveda

• The formulation is clinically proven and provides fast relief against acute cough and throat irritation

Patanjali Ayurveda Limited

Ø Patanjali Ayurved Limited is an Indian FMCG company. Manufacturing units and headquarters are located in the industrial area of Haridwar while the registered office is located at Delhi

Ø The company manufactures mineral and herbal products. It also has manufacturing units in Nepal under the trademark Nepal Gramudhyog

Ø Patanjali is the fastest growing FMCG company in India. It is valued at ₹30 billion(US$470 million) and revenues of ₹5,000 crores (US$780 million) for the year 2015–16

Ø Ramdev established the Patanjali Ayurved Limited in 2006 along with Acharya Balakrishna with the objective of establishing science of Ayurveda in accordance and coordination with the latest technology and ancient wisdom

Year	Revenues (In Rs Crore)
2009-10	165
2010-11	317
2011-12	446
2012-13	850
2013-14	1200
2014-15	2006
2015-16	5008
2016- 17	10561

ASHVASHILA (CAPSULE)

• Patanjali Ashvashila capsule is a combination of Ashwagandha and Shilajit which makes it a powerful remedy in Sexual weakness, fatigue, stress, generalized weakness, asthma, allergy, diabetes, diabetic neuropathy, urinary disorders and loss of immunity

Ashwagandha (CAPSULE)

Ø It is beneficial for fatigue, restiveness and general weakness. It also treats muscles deficiency, gastric problems, arthritis and others. Helps to increase energy of body cells naturally. Ashwagandha is a natural herbal tonic for increasing memory and brain power

Research Institutions/Centres

Name	City
CCRAS (Central Council for Research in Ayurveda and Siddha)	New Delhi
NBRI (National Botanical Research Institute)	Lucknow
National Institute of Ayurveda	Jaipur
National Medicinal Plants Board	New Delhi
Regional Medical Research Centre	Belgaum
CDRI (Central Drug Research Institute)	Lucknow
National Buraeu of Plant Genetic Resources	New Delhi
FRLHT (Foundation for Revitalisation of Local Health Traditions)	Bangalore

FRLHT

Ø Foundation for Revitalisation of Local Health Traditions (FRLHT) is a registered Public Trust and Charitable Society, which started its activities in 1993

Ø Indian ministry of Science and Technology recognizes FRLHT as a scientific and research organization

Ø Ministry of Environment and Forests has designated FRLHT as a National Centre of Excellence for medicinal plants and traditional knowledge

Ø The foundation plans to "revitalize Indian medical heritage” through creative applications of traditional health sciences for enhancing the quality of health care in rural and urban India and globally

Ø Conservation of threatened natural resources in use by Indian Systems of Medicine

Ø Generate well trained human resources with knowledge and skills to disseminate the traditional health sciences both in India and globally.

CCRAS

Ø Central Council for Research in Ayurvedic Sciences (CCRAS) is an autonomous body of the Ministry of AYUSH (Ayurveda, Yoga & Naturopathy, Unani, Siddha and Homeopathy), Government of India.

Ø It is an apex body in India for the formulation, coordination, development and promotion of research on scientific lines in Ayurveda

Research activities:

Ø Medicinal plant research

Ø Clinical research

Ø Drug standardization

Ø Tribal health care research

Ø Data base on medicinal plants

Summary

Ø Himalaya Drug Company – Manal, Liv 52, Bonnisan, Mentat, Septilin

Ø Dabur Pharmaceuticals - Chyawanprash, Hajmola, Pudinhara

Ø Patanjali - Ashwashila, aswagandha, lauh bhasma, Spatica bhasma

Ø FRLHT -a registered Public Trust and Charitable Society, 1993