Emetics - Mechanism of action, Indications, Contraindication, Adverse effects and Drug interactions

Emetics

Emetics are the drugs which produce vomiting.

Mechanism of action

They stimulate the chemoreceptor trigger zone and gastric mucosa to induce vomiting.

Drug example and doses

Apomorphine - 5mg IM

Copper sulfate - Given in water every 5 min. until emesis occur.

Sodium chloride (Nacl) – 2 Table spoon of NaCl in glass of warm water.

Ipecac syrup - 15 - 30ml (followed by 200ml of water.

Indications / Uses

To induce vomiting.

To treat poisoning.

Treatment of overdose of Drug.

Contraindication / Precautions

History of seizures.

Semi-comatose or unconscious patient.

Ingested caustic substance or petroleum products.

Adverse effects

Arrhythmias.

Cardiotoxicity.

Diarrhea.

Drowsiness.

Drug interactions

Emetic reduce their effects when used with activated Charcoal.

Emetics Notes PDF